OBJECTIVE : Raise the Fg
concentration (in g/L)
Average patient weight
(in kg)
Comparison based on official product description of the cost of 2 fibrinogen concentrates (LFB vs. CSL) with different recovery, for patients with congenital Fibrinogen deficiency. Only the LFB's Fibrinogen has a specific posology for pediatric use which is not comparable with competitors due to a lack of data:
For the initial dose: treatment of bleeding and prophylaxis in patients with congenital hypo- or afibrinogenaemia and known bleeding tendency. 1.2.3.4.5
In emergency case: if the patient's fibrinogen level is not known. 1.2.3.4.5
FIBRINOGEN
FIBRINOGEN
FIBRINOGEN
Quantity of fibrinogen per vial
1.5 g
OBJECTIVE : Raise the Fg
concentration (in g/L)
Average patient weight
(in kg)
FIBRINOGEN
FIBRINOGEN
FIBRINOGEN
Quantity of Fg needed to achieve the objective (in g)
Quantity of LFB Fibrinogen needed to achieved the objective (g):
amount to be injected (g) = desired level increase (g/L) x 0,043 x body weight (kg) 1, 2
Quantity of CSL Fibrinogen needed to achieved the objective (g) :
amount to be injected (g) = desired level increase (g/L) x 1/17 x body weight (kg) 3, 4
Quantity of Octapharma Fibrinogen needed to achieved the objective (g) :
amount to be injected (g) = desired level increase (g/L) x 1/18 x body weight (kg) 5
0
0
0
Number of vial(s) entirely needed
% of additional vial partially used
40%
20%
0%
Number of vial(s) needed
Equivalent in Fg increase (in g/L)
22 g/L
15 g/L
15 g/L
Cost of vial (no currency)
Total cost (no currency)
0
0
0
Fibrinogen is LFB Fibrinogen
CSL Fibrinogen is LFB Fibrinogen
RE-CALCULATE
OCTA Fibrinogen is LFB Fibrinogen
Average patient weight
(in kg)
FIBRINOGEN
FIBRINOGEN
FIBRINOGEN
Quantity of Fg needed to achieve the objective (in g)
Quantity of LFB Fibrinogen needed to achieved the objective (g):
amount to be injected (g) = 0,05 x body weight (kg) 1, 2
Quantity of CSL Fibrinogen needed to achieved the objective (g) :
amount to be injected (g) = 0,07 x body weight (kg) 3, 4
Quantity of Octapharma Fibrinogen needed to achieved the objective (g) :
amount to be injected (g) = 0,06 x body weight (kg) 5
0
0
0
Number of vial(s) entirely needed
% of additional vial partially used
Number of vial(s) needed
Equivalent in Fg increase (in g/L)
0 g/L
0 g/L
0 g/L
Cost of vial (no currency)
Total cost (no currency)
0
0
0
Fibrinogen is LFB Fibrinogen
CSL Fibrinogen is LFB Fibrinogen
RE-CALCULATE
OCTA Fibrinogen is LFB Fibrinogen